P-Cool Cream 20 gm is a combination of three drugs, namely: Calamine (anti-pruritic), phenylephrine (sympathomimetic agent), and lidocaine (local anaesthetic). Calamine has antiseptic and anti-pruritic properties. Phenylephrine decreases swelling by shrinking the blood vessels in the affected area. Lidocaine blocks the pain signals from the nerves to the brain, thereby decreases the sensation of pain.
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